472 research outputs found
On Measuring Non-Recursive Trade-Offs
We investigate the phenomenon of non-recursive trade-offs between
descriptional systems in an abstract fashion. We aim at categorizing
non-recursive trade-offs by bounds on their growth rate, and show how to deduce
such bounds in general. We also identify criteria which, in the spirit of
abstract language theory, allow us to deduce non-recursive tradeoffs from
effective closure properties of language families on the one hand, and
differences in the decidability status of basic decision problems on the other.
We develop a qualitative classification of non-recursive trade-offs in order to
obtain a better understanding of this very fundamental behaviour of
descriptional systems
Eliciting a predatory response in the eastern corn snake (Pantherophis guttatus) using live and inanimate sensory stimuli: implications for managing invasive populations
North America's Eastern corn snake (Pantherophis guttatus) has been introduced to several islands throughout the Caribbean and Australasia where it poses a significant threat to native wildlife. Invasive snake control programs often involve trapping with live bait, a practice that, as well as being costly and labour intensive, raises welfare and ethical concerns. This study assessed corn snake response to live and inanimate sensory stimuli in an attempt to inform possible future trapping of the species and the development of alternative trap lures. We exposed nine individuals to sensory cues in the form of odour, visual, vibration and combined stimuli and measured the response (rate of tongue-flick [RTF]). RTF was significantly higher in odour and combined cues treatments, and there was no significant difference in RTF between live and inanimate cues during odour treatments. Our findings suggest chemical cues are of primary importance in initiating predation and that an inanimate odour stimulus, absent of simultaneous visual and vibratory cues, is a potential low-cost alternative trap lure for the control of invasive corn snake populations
Experimental demonstration of quantum correlations over more than 10 km
Energy and time entangled photons at a wavelength of 1310 nm are produced by
parametric downconversion in a KNbO3 crystal and are sent into all-fiber
interferometers using a telecom fiber network. The two interferometers of this
Franson-type test of the Bell-inequality are located 10.9 km apart from one
another. Two-photon fringe visibilities of up to 81.6 % are obtained. These
strong nonlocal correlations support the nonlocal predictions of quantum
mechanics and provide evidence that entanglement between photons can be
maintained over long distances.Comment: 5 pages, REVTeX, 3 postscript figures include
Quantum magnetism and criticality
Magnetic insulators have proved to be fertile ground for studying new types
of quantum many body states, and I survey recent experimental and theoretical
examples. The insights and methods transfer also to novel superconducting and
metallic states. Of particular interest are critical quantum states, sometimes
found at quantum phase transitions, which have gapless excitations with no
particle- or wave-like interpretation, and control a significant portion of the
finite temperature phase diagram. Remarkably, their theory is connected to
holographic descriptions of Hawking radiation from black holes.Comment: 39 pages, 10 figures, review article for non-specialists; (v2) added
clarifications and references; (v3) minor corrections; (v4) added footnote on
hydrodynamic long-time tail
Eosinophilic myocarditis mimicking acute coronary syndrome secondary to idiopathic hypereosinophilic syndrome: a case report
<p>Abstract</p> <p>Introduction</p> <p>Eosinophilic myocarditis is a rare form of myocarditis. It is characterized pathologically by diffuse or focal myocardial inflammation with eosinophilic infiltration, often in association with peripheral blood eosinophilia. We report a case of eosinophilic myocarditis secondary to hypereosinophilic syndrome.</p> <p>Case presentation</p> <p>A 74-year-old Caucasian woman with a history of asthma, paroxysmal atrial fibrillation, stroke and coronary artery disease presented to the emergency department of our hospital with chest pain. Evaluations revealed that she had peripheral blood eosinophilia and elevated cardiac enzymes. Electrocardiographic findings were nonspecific. Her electrocardiographic finding and elevated cardiac enzymes pointed to a non-ST-elevated myocardial infarction. Echocardiogram showed a severe decrease in the left ventricular systolic function. Coronary angiogram showed nonobstructive coronary artery disease. She then underwent cardiac magnetic resonance imaging, which showed neither infiltrative myocardial diseases nor any evidence of infarction. This was followed by an endomyocardial biopsy which was consistent with eosinophilic myocarditis. Hematologic workup regarding her eosinophilia was consistent with hypereosinophilic syndrome. After being started on steroid therapy, her peripheral eosinophilia resolved and her symptoms improved. Her left ventricular ejection fraction, however, did not improve.</p> <p>Conclusion</p> <p>Eosinophilic myocarditis can present like an acute myocardial infarction and should be considered in the differential diagnosis of acute coronary syndrome in patients with a history of allergy, asthma or acute reduction of the left ventricular function with or without peripheral eosinophilia.</p
Condensed matter and AdS/CFT
I review two classes of strong coupling problems in condensed matter physics,
and describe insights gained by application of the AdS/CFT correspondence. The
first class concerns non-zero temperature dynamics and transport in the
vicinity of quantum critical points described by relativistic field theories. I
describe how relativistic structures arise in models of physical interest,
present results for their quantum critical crossover functions and
magneto-thermoelectric hydrodynamics. The second class concerns symmetry
breaking transitions of two-dimensional systems in the presence of gapless
electronic excitations at isolated points or along lines (i.e. Fermi surfaces)
in the Brillouin zone. I describe the scaling structure of a recent theory of
the Ising-nematic transition in metals, and discuss its possible connection to
theories of Fermi surfaces obtained from simple AdS duals.Comment: 39 pages, 12 figures; Lectures at the 5th Aegean summer school, "From
gravity to thermal gauge theories: the AdS/CFT correspondence", and the De
Sitter Lecture Series in Theoretical Physics 2009, University of Groninge
Renewable Energy (RE): Bioenergy -Feedstocks and Pretreatment-
The Department for Pulsed Power Technology is focusing on research and development of pulsed power technologies and related applications. The applications involves the electroporation of biological cells for extraction of cell contents (PEF- process), dewatering and drying of green biomass, pre-treatment of micro algae for energetic use and sustainable reduction of bacteria in contaminated effluents. Another key research topic is devoted to the development of corrosion barriers and materials for improved compatibility of structural materials in contact with liquid metal coolants. This year\u27s report focuses primarily on the activities and results of ongoing third-party funded projects of the department
Peptide YY ablation in mice leads to the development of hyperinsulinaemia and obesity
Aims/hypothesis. Obese people exhibit reduced circulating peptide YY (PYY) levels, but it is unclear whether this is a consequence or cause of obesity. We therefore investigated the effect of Pyy ablation on energy homeostasis.
Methods. Body composition, i.p. glucose tolerance, food intake and hypothalamic neuropeptide expression were determined in Pyy knock-out and wild-type mice on a normal or high-fat diet. Results. Pyy knock-out significantly increased bodyweight and increased fat mass by 50% in aged females on a normal diet. Male chow-fed Pyy −/− mice were resistant to obesity but became significantly fatter and glucose-intolerant compared with wild-types when fed a high-fat diet. Pyy knock-out animals exhibited significantly elevated fasting or glucose-stimulated serum insulin concentrations vs wild-types, with no increase in basal or fasting-induced food intake. Pyy knock-out decreased or had no effect on neuropeptide Y expression in the arcuate nucleus of the hypothalamus, and significantly increased proopiomelanocortin expression in this region. Male but not female knock-outs exhibited significantly increased growth hormone-releasing hormone expression in the ventromedial hypothalamus and significantly elevated serum IGF-I and testosterone levels. This sex difference in activation of the hypothalamo–pituitary somatotrophic axis by Pyy ablation may contribute to the resistance of chow-fed male knock-outs to late-onset obesity.
Conclusions/interpretation. PYY signalling is important in the regulation of energy balance and glucose homeostasis, possibly via regulation of insulin release. Therefore reduced PYY levels may predispose to the development of obesity, particularly with ageing or under conditions of high-fat feeding
Distinct Functions of Period2 and Period3 in the Mouse Circadian System Revealed by In Vitro Analysis
The mammalian circadian system, which is composed of a master pacemaker in the suprachiasmatic nuclei (SCN) as well as other oscillators in the brain and peripheral tissues, controls daily rhythms of behavior and physiology. Lesions of the SCN abolish circadian rhythms of locomotor activity and transplants of fetal SCN tissue restore rhythmic behavior with the periodicity of the donor's genotype, suggesting that the SCN determines the period of the circadian behavioral rhythm. According to the model of timekeeping in the SCN, the Period (Per) genes are important elements of the transcriptional/translational feedback loops that generate the endogenous circadian rhythm. Previous studies have investigated the functions of the Per genes by examining locomotor activity in mice lacking functional PERIOD proteins. Variable behavioral phenotypes were observed depending on the line and genetic background of the mice. In the current study we assessed both wheel-running activity and Per1-promoter-driven luciferase expression (Per1-luc) in cultured SCN, pituitary, and lung explants from Per2−/− and Per3−/− mice congenic with the C57BL/6J strain. We found that the Per2−/− phenotype is enhanced in vitro compared to in vivo, such that the period of Per1-luc expression in Per2−/− SCN explants is 1.5 hours shorter than in Per2+/+ SCN, while the free-running period of wheel-running activity is only 11 minutes shorter in Per2−/− compared to Per2+/+ mice. In contrast, circadian rhythms in SCN explants from Per3−/− mice do not differ from Per3+/+ mice. Instead, the period and phase of Per1-luc expression are significantly altered in Per3−/− pituitary and lung explants compared to Per3+/+ mice. Taken together these data suggest that the function of each Per gene may differ between tissues. Per2 appears to be important for period determination in the SCN, while Per3 participates in timekeeping in the pituitary and lung
Presence of depression and anxiety before and after coronary artery bypass graft surgery and their relationship to age
<p>Abstract</p> <p>Background</p> <p>Scientific literature on depression and anxiety in patients with coronary heart disease (CHD) consistently reports data of elevated anxiety and depression scores indicating clinically relevant quantities of these psychopathological conditions. Depression is considered to be a risk factor for the development of CHD and deteriorates the outcome after cardiac rehabilitation efforts. The aim of our study was to evaluate the presence of clinically relevant anxiety and depression in patients before and after coronary artery bypass grafting (CABG). Additionally we evaluated their relationship to age because of the increasing number of elderly patients undergoing CABG surgery.</p> <p>Methods</p> <p>One hundred and forty-two consecutive patients who underwent CABG in our hospital were asked to fill in the "Hospital Anxiety and Depression Scale – German Version (HADS)" to measure depression and anxiety scores two days before and ten days after CABG surgery. Differences between these pre- and post-surgical scores were then calculated as means for changes, and the amount of elevated scores were appraised. In order to investigate the relationship between age and anxiety and depression, respectively, Spearman correlations between age and the difference scores were calculated. In addition, ANOVA procedures with the factor "age group" and McNemar tests were calculated. Therefore the sample was divided into four equally sized age groups.</p> <p>Results</p> <p>25.8% of the patients were clinically depressed before and 17.5% after surgery; 34.0% of the patients were clinically anxious before and 24.7% after surgery. This overall change is not significant. We found a significant negative correlation between age and the difference between the two time points for anxiety (Spearman rho = -.218; p = 0.03), but not for depression (Spearman rho = -.128; p = 0.21). ANOVA and McNemar-Tests revealed that anxiety scores and the number of patients high in anxiety declined statistically meaningful only in the youngest patient group. Such a relationship could not be found for depression.</p> <p>Conclusion</p> <p>Our data show a relationship between age and anxiety. Younger patients are more anxious before CABG surgery than older ones and show a decline in symptoms while elderly patients show hardly any change.</p
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